HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: MCR1 (P36060)
NADH-cytochrome b5 reductase 2 (EC 1.6.2.2) (Mitochondrial cytochrome b reductase) (p34/p32) [Cleaved into: NADH-cytochrome b5 reductase p34 form; NADH-cytochrome b5 reductase p32 form]
Gene: MCR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	35876647, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 302
+	Sc
		490879 HSP71_YEAST (1-639): 0: 969: 97.04		MCR1_YEAST (1-302): 9.84e-103: 304: 100.00
+	Sc
		605333 HSP74_YEAST (1-639): 0: 960: 81.62		MCR1_YEAST (1-302): 9.84e-103: 304: 100.00
+	Sc
		491084 HSP71_YEAST (1-639): 0: 969: 97.04		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Sc
		492964 HSP71_YEAST (1-639): 0: 969: 97.04		PGA3_YEAST (28-302): 4.69e-77: 239: 31.64
+	Hs
		335349 HSP7C_HUMAN (2-639): 0: 948: 74.34		NB5R3_HUMAN (28-302): 2.31e-85: 259: 29.00
+	Hs
		564022 HSP76_HUMAN (4-639): 0: 952: 70.58		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Sc
		493853 HSP72_YEAST (1-639): 0: 935: 100.00		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Hs
		718466 HSP72_HUMAN (2-639): 0: 933: 71.23		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Sc
		491273 HSP71_YEAST (1-639): 0: 969: 97.04		FHP_YEAST (48-300): 1.43e-46: 162: 16.54
+	Sc
		494008 HSP72_YEAST (1-639): 0: 935: 100.00		FHP_YEAST (48-300): 1.43e-46: 162: 16.54