HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: FES1 (P38260)
Hsp70 nucleotide exchange factor FES1 (Factor exchange for SSA1 protein 1)
Gene: FES1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.728

Property	Details
Experiments	31242183, 37968396, 22635919, 24671421, 19536198, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 290
+	Sc
		491027 HSP71_YEAST (1-639): 0: 969: 97.04		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sc
		605341 HSP74_YEAST (1-639): 0: 960: 81.62		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sp
		195082 HSP71_SCHPO (1-639): 0: 963: 78.42		FES1_SCHPO (1-237): 8.83e-52: 173: 29.63
+	Dm
		947885 HSP70_DROME (3-639): 0: 933: 69.74		Q95RI2_DROME (1-247): 8.95e-59: 191: 20.40
+	Hs
		714085 HS71L_HUMAN (2-639): 0: 959: 72.08		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		564199 HSP76_HUMAN (4-639): 0: 952: 70.58		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		504872 HSP7C_HUMAN (2-639): 0: 948: 74.34		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		483807 HS71B_HUMAN (2-639): 0: 940: 73.01		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		871809 HSP72_HUMAN (2-639): 0: 933: 71.23		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13