HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	22940862, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 993
+	Sc
		491127 HSP71_YEAST (1-639): 0: 969: 97.04		RPN1_YEAST (1-993): 0: 1053: 100.00
+	Hs
		1027678 Q53FC7_HUMAN (4-639): 0: 948: 69.95		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Hs
		504012 HSP7C_HUMAN (2-639): 0: 948: 74.34		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Hs
		871554 HSP72_HUMAN (2-639): 0: 933: 71.23		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Ce
		450539 HSP1_CAEEL (3-639): 0: 934: 75.82		Q9GZH5_CAEEL (8-990): 0: 995: 37.61
+	Sc
		490667 HSP71_YEAST (1-639): 0: 969: 97.04		RPN2_YEAST (52-815): 2.95e-177: 542: 15.54
+	Sc
		493479 HSP72_YEAST (1-639): 0: 935: 100.00		RPN2_YEAST (52-815): 2.95e-177: 542: 15.54