HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: KOG1 (P38873)
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)
Gene: KOG1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	33566094, 22043304, 19536198, 16429126
Identification Methods	protein complementation assay, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 1557
+	Sc
		450042 HSP73_YEAST (1-639): 0: 961: 78.89		KOG1_YEAST (1-1557): 0: 1428: 100.00
+	Hs
		871663 HSP72_HUMAN (2-639): 0: 933: 71.23		RPTOR_HUMAN (20-1552): 0: 1188: 28.59
+	Hs
		504344 HSP7C_HUMAN (2-639): 0: 948: 74.34		WDR5B_HUMAN (1108-1430): 3.23e-64: 223: 11.64
+	At
		1275309 HS704_ARATH (2-639): 0: 955: 70.50		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	At
		612312 HS701_ARATH (2-639): 0: 952: 71.16		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	At
		250065 HSP7C_ARATH (2-639): 0: 940: 70.65		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	At
		1275322 HSP7E_ARATH (3-639): 0: 938: 70.45		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	At
		612335 HS702_ARATH (2-639): 0: 934: 71.56		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	Hs
		503614 HSP7C_HUMAN (2-639): 0: 948: 74.34		LIS1_HUMAN (1348-1552): 7.62e-38: 149: 9.80
+	Hs
		503743 HSP7C_HUMAN (2-639): 0: 948: 74.34		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Hs
		714020 HS71L_HUMAN (2-639): 0: 959: 72.08		POC1A_HUMAN (1142-1317): 1.14e-18: 92.3: 11.74
+	Hs
		564125 HSP76_HUMAN (4-639): 0: 952: 70.58		POC1A_HUMAN (1142-1317): 1.14e-18: 92.3: 11.74
+	Hs
		504412 HSP7C_HUMAN (2-639): 0: 948: 74.34		POC1A_HUMAN (1142-1317): 1.14e-18: 92.3: 11.74
+	Sc
		490241 HSP71_YEAST (1-639): 0: 969: 97.04		TUP1_YEAST (1267-1526): 3.96e-10: 66.8: 18.25
+	Hs
		503817 HSP7C_HUMAN (2-639): 0: 948: 74.34		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Sc
		493119 HSP72_YEAST (1-639): 0: 935: 100.00		TUP1_YEAST (1267-1526): 3.96e-10: 66.8: 18.25