HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: NDC80 (P40460)
Kinetochore protein NDC80 (80 kDa spindle component protein) (Nuclear division cycle protein 80) (Two-hybrid interaction with DMC1 protein 3)
Gene: NDC80

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	22908312, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 691
+	Sc
		491434 HSP71_YEAST (1-639): 0: 969: 97.04		NDC80_YEAST (1-691): 1.63e-81: 274: 100.00
+	Sc
		450067 HSP73_YEAST (1-639): 0: 961: 78.89		NDC80_YEAST (1-691): 1.63e-81: 274: 100.00
+	Hs
		504448 HSP7C_HUMAN (2-639): 0: 948: 74.34		DLG5_HUMAN (281-690): 1.87e-21: 102: 9.71
+	Sc
		490455 HSP71_YEAST (1-639): 0: 969: 97.04		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71
+	Hs
		502805 HSP7C_HUMAN (2-639): 0: 948: 74.34		LAMC1_HUMAN (251-652): 1.04e-12: 73.8: 14.09
+	Hs
		148449 HS71L_HUMAN (2-639): 0: 959: 72.08		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		504493 HSP7C_HUMAN (2-639): 0: 948: 74.34		MY18A_HUMAN (264-674): 1.96e-12: 73: 16.20
+	Hs
		504591 HSP7C_HUMAN (2-639): 0: 948: 74.34		CFA57_HUMAN (266-645): 2.49e-11: 69.2: 12.31
+	Hs
		148367 HSP76_HUMAN (4-639): 0: 952: 70.58		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		148327 HSP7C_HUMAN (2-639): 0: 948: 74.34		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		504067 HSP7C_HUMAN (2-639): 0: 948: 74.34		DCTN1_HUMAN (414-689): 2.74e-09: 62.6: 12.41
+	Sc
		493298 HSP72_YEAST (1-639): 0: 935: 100.00		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71
+	Hs
		148576 HSP72_HUMAN (2-639): 0: 933: 71.23		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16