HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: PPID (P53691)
Peptidyl-prolyl cis-trans isomerase CPR6 (PPIase CPR6) (EC 5.2.1.8) (Rotamase CPR6)
Gene: CPR6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006457 - protein folding GO:0042026 - protein refolding and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 371
+	Hs
		503968 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPID_HUMAN (2-371): 4.59e-130: 379: 43.51
+	Sc
		491994 HSP71_YEAST (1-639): 0: 969: 97.04		PPID_YEAST (1-371): 4.51e-121: 356: 100.00
+	Ca
		804455 HSP72_CANAL (1-639): 0: 972: 84.19		PPID_CANAL (1-371): 1.5e-119: 352: 51.07
+	Ca
		784139 HSP71_CANAL (1-603): 0: 942: 85.17		PPID_CANAL (1-371): 1.5e-119: 352: 51.07
+	Sc
		491698 HSP71_YEAST (1-639): 0: 969: 97.04		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		450095 HSP73_YEAST (1-639): 0: 961: 78.89		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		605366 HSP74_YEAST (1-639): 0: 960: 81.62		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		494338 HSP72_YEAST (1-639): 0: 935: 100.00		CYP7_YEAST (1-371): 2.41e-92: 283: 38.38
+	Sc
		490493 HSP71_YEAST (1-639): 0: 969: 97.04		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Sc
		490206 HSP71_YEAST (1-639): 0: 969: 97.04		CYPH_YEAST (5-174): 3.55e-77: 236: 55.88
+	Sc
		449937 HSP73_YEAST (1-639): 0: 961: 78.89		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Sc
		605308 HSP74_YEAST (1-639): 0: 960: 81.62		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Hs
		503513 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPIF_HUMAN (3-174): 2.09e-77: 238: 54.07
+	Sc
		493331 HSP72_YEAST (1-639): 0: 935: 100.00		CYPC_YEAST (5-174): 2.1e-77: 238: 55.88
+	Sc
		493093 HSP72_YEAST (1-639): 0: 935: 100.00		CYPH_YEAST (5-174): 3.55e-77: 236: 55.88