HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: APJ1 (P53940)
J domain-containing protein APJ1
Gene: APJ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17892321
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0042026 - protein refolding and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Sc			1 528
+	Sc
		492073 HSP71_YEAST (1-639): 0: 969: 97.04		APJ1_YEAST (1-528): 0: 522: 100.00
+	Sc
		450143 HSP73_YEAST (1-639): 0: 961: 78.89		APJ1_YEAST (1-528): 0: 522: 100.00
+	Sc
		605378 HSP74_YEAST (1-639): 0: 960: 81.62		APJ1_YEAST (1-528): 0: 522: 100.00
+	Hs
		681341 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJA1_HUMAN (1-484): 1.22e-126: 377: 26.88
+	Hs
		564015 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJA1_HUMAN (1-484): 1.22e-126: 377: 26.88
+	Sc
		490460 HSP71_YEAST (1-639): 0: 969: 97.04		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Sc
		449929 HSP73_YEAST (1-639): 0: 961: 78.89		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Sc
		605303 HSP74_YEAST (1-639): 0: 960: 81.62		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Hs
		243312 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJA2_HUMAN (2-455): 2.4e-113: 343: 27.89
+	Hs
		714049 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJA3_HUMAN (5-467): 1.5e-111: 341: 21.14
+	Hs
		243284 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJA2_HUMAN (2-455): 2.4e-113: 343: 27.89
+	Sc
		490428 HSP71_YEAST (1-639): 0: 969: 97.04		SCJ1_YEAST (6-425): 6.87e-96: 297: 24.59
+	Sp
		251814 HSP71_SCHPO (1-639): 0: 963: 78.42		MAS5_SCHPO (1-460): 6.51e-96: 299: 25.52
+	Hs
		714088 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB4_HUMAN (5-428): 2.53e-97: 300: 21.46
+	Sp
		223772 HSP72_SCHPO (1-639): 0: 958: 77.74		MAS5_SCHPO (1-460): 6.51e-96: 299: 25.52
+	Hs
		279280 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB5_HUMAN (5-427): 3.38e-96: 297: 22.70
+	Hs
		636256 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB1_HUMAN (5-427): 1.1e-95: 295: 21.93
+	Hs
		279274 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB5_HUMAN (5-427): 3.38e-96: 297: 22.70
+	Hs
		564008 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB1_HUMAN (5-427): 1.1e-95: 295: 21.93
+	Sc
		491252 HSP71_YEAST (1-639): 0: 969: 97.04		XDJ1_YEAST (7-411): 1.85e-27: 117: 28.90