HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: PROA (P54885)
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (GSA dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)
Gene: PRO2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 456
+	Sc
		491355 HSP71_YEAST (1-639): 0: 969: 97.04		ALDH5_YEAST (2-412): 5.8e-136: 402: 14.16
+	Sc
		491624 HSP71_YEAST (1-639): 0: 969: 97.04		ALDH4_YEAST (2-414): 2.17e-133: 396: 14.95
+	Sc
		491740 HSP71_YEAST (1-639): 0: 969: 97.04		ALDH2_YEAST (3-424): 1.25e-128: 383: 15.71
+	Sc
		492111 HSP71_YEAST (1-639): 0: 969: 97.04		PROA_YEAST (1-456): 2.74e-127: 378: 100.00
+	Sc
		492096 HSP71_YEAST (1-639): 0: 969: 97.04		ALDH3_YEAST (3-424): 2.12e-125: 375: 14.86
+	Sc
		494075 HSP72_YEAST (1-639): 0: 935: 100.00		ALDH5_YEAST (2-412): 5.8e-136: 402: 14.16
+	Sc
		490959 HSP71_YEAST (1-639): 0: 969: 97.04		UGA2_YEAST (1-428): 4.66e-121: 363: 12.10
+	Sc
		494285 HSP72_YEAST (1-639): 0: 935: 100.00		ALDH4_YEAST (2-414): 2.17e-133: 396: 14.95
+	Hs
		503757 HSP7C_HUMAN (2-639): 0: 948: 74.34		P5CS_HUMAN (3-451): 1.19e-120: 372: 40.31
+	Sc
		494368 HSP72_YEAST (1-639): 0: 935: 100.00		ALDH2_YEAST (3-424): 1.25e-128: 383: 15.71
+	Hs
		564040 HSP76_HUMAN (4-639): 0: 952: 70.58		AL3A2_HUMAN (4-401): 2.43e-61: 208: 17.97
+	Hs
		503715 HSP7C_HUMAN (2-639): 0: 948: 74.34		AL3A2_HUMAN (4-401): 2.43e-61: 208: 17.97
+	Hs
		713921 HS71L_HUMAN (2-639): 0: 959: 72.08		AL3B1_HUMAN (1-401): 1.93e-45: 166: 16.93
+	Hs
		503619 HSP7C_HUMAN (2-639): 0: 948: 74.34		AL3B1_HUMAN (1-401): 1.93e-45: 166: 16.93
+	Hs
		483779 HS71B_HUMAN (2-639): 0: 940: 73.01		AL3B1_HUMAN (1-401): 1.93e-45: 166: 16.93
+	Hs
		795516 HSP72_HUMAN (2-639): 0: 933: 71.23		AL3B1_HUMAN (1-401): 1.93e-45: 166: 16.93
+	Hs
		503658 HSP7C_HUMAN (2-639): 0: 948: 74.34		AL3B2_HUMAN (113-418): 4.11e-32: 127: 16.09