HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: PKH1 (Q03407)
Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1)
Gene: PKH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Sc			1 766
+	Sc
		492254 HSP71_YEAST (1-639): 0: 969: 97.04		PKH1_YEAST (1-766): 0: 623: 100.00
+	Sc
		450168 HSP73_YEAST (1-639): 0: 961: 78.89		PKH1_YEAST (1-766): 0: 623: 100.00
+	Hs
		564016 HSP76_HUMAN (4-639): 0: 952: 70.58		AKT1_HUMAN (10-454): 1.82e-144: 434: 22.22
+	Hs
		503528 HSP7C_HUMAN (2-639): 0: 948: 74.34		AKT1_HUMAN (10-454): 1.82e-144: 434: 22.22
+	Mm
		554912 HS71A_MOUSE (2-639): 0: 948: 72.39		KPCE_MOUSE (28-460): 6.97e-140: 431: 22.45
+	Hs
		503922 HSP7C_HUMAN (2-639): 0: 948: 74.34		KPCE_HUMAN (28-460): 2.59e-139: 430: 22.22
+	Sc
		412627 HSP71_YEAST (1-639): 0: 969: 97.04		KAPA_YEAST (47-446): 5.01e-134: 404: 26.63
+	Hs
		254440 HSP7C_HUMAN (2-639): 0: 948: 74.34		ROCK2_HUMAN (118-580): 7.33e-123: 402: 25.11
+	Sc
		412628 HSP72_YEAST (1-639): 0: 935: 100.00		KAPA_YEAST (47-446): 5.01e-134: 404: 26.63
+	Hs
		564201 HSP76_HUMAN (4-639): 0: 952: 70.58		KS6B2_HUMAN (119-492): 1.66e-123: 380: 28.54
+	Hs
		504896 HSP7C_HUMAN (2-639): 0: 948: 74.34		KS6B2_HUMAN (119-492): 1.66e-123: 380: 28.54
+	Hs
		564041 HSP76_HUMAN (4-639): 0: 952: 70.58		KS6A3_HUMAN (63-404): 2.7e-101: 330: 22.95
+	Hs
		503719 HSP7C_HUMAN (2-639): 0: 948: 74.34		KS6A3_HUMAN (63-404): 2.7e-101: 330: 22.95
+	Hs
		564080 HSP76_HUMAN (4-639): 0: 952: 70.58		KS6A1_HUMAN (125-395): 1.14e-89: 299: 28.37
+	Hs
		504119 HSP7C_HUMAN (2-639): 0: 948: 74.34		KS6A1_HUMAN (125-395): 1.14e-89: 299: 28.37
+	Hs
		182080 HSP76_HUMAN (4-639): 0: 952: 70.58		PDPK1_HUMAN (123-412): 1.77e-80: 270: 46.28
+	Hs
		182076 HSP7C_HUMAN (2-639): 0: 948: 74.34		PDPK1_HUMAN (123-412): 1.77e-80: 270: 46.28
+	Sc
		492245 HSP71_YEAST (1-639): 0: 969: 97.04		PKH3_YEAST (124-398): 2.34e-63: 229: 43.69
+	Sc
		450166 HSP73_YEAST (1-639): 0: 961: 78.89		PKH3_YEAST (124-398): 2.34e-63: 229: 43.69
+	Hs
		483772 HS71A_HUMAN (2-639): 0: 940: 73.01		ST38L_HUMAN (119-397): 2.34e-43: 165: 32.26