HitPredict

Interactor 1: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 105 Hs			1 1480
+	Hs
		529425 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528451 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		423122 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		CFTR_HUMAN (1-1480): 0: 1031: 100.00