HitPredict

Interactor 1: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Interactor 2: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24976139
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 105 Hs			1 435
+	Hs
		423138 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		202588 TXNL1_HUMAN (2-105): 1.99e-36: 126: 40.39		PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98
+	Hs
		570556 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98
+	Hs
		577042 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		PTPRA_HUMAN (12-278): 9.1e-105: 330: 31.62
+	Hs
		531846 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		PTPRO_HUMAN (20-274): 4.19e-48: 178: 38.31
+	Hs
		423243 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		PTPRO_HUMAN (20-274): 4.19e-48: 178: 38.31
+	Hs
		495472 THIO_HUMAN (1-105): 6.33e-41: 132: 100.00		PTN6_HUMAN (342-432): 1.75e-12: 71.2: 10.48
+	Hs
		531930 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		PTPRU_HUMAN (341-434): 6.63e-17: 85.4: 13.59
+	Hs
		423314 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		PTPRU_HUMAN (341-434): 6.63e-17: 85.4: 13.59