HitPredict

Interactor 1: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21800051
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 105 Hs			1 329
+	Hs
		202698 TXNL1_HUMAN (2-105): 1.99e-36: 126: 40.39		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		1306360 THIOM_HUMAN (5-105): 2.33e-34: 117: 35.92		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Dm
		715046 THIO2_DROME (1-105): 5.65e-36: 119: 49.06		UCHL_DROME (8-228): 2.12e-79: 243: 24.78
+	Hs
		423112 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		UCHL1_HUMAN (10-226): 1.03e-74: 231: 22.22
+	Hs
		495580 THIO_HUMAN (1-105): 6.33e-41: 132: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1240399 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		531922 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		423310 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29