HitPredict

Interactor 1: TWIST (P10627)
Protein twist
Gene: twi

Interactor 2: UBX (P83949)
Homeotic protein ultrabithorax
Gene: UBX

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30247122, 25869471
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0005634 - nucleus GO:0007501 - mesodermal cell fate specification GO:0007507 - heart development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 490 Dm			1 389
+	Dm
		496117 TWIST_DROME (1-490): 3.94e-162: 469: 100.00		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		367171 TWIST_DROME (1-490): 3.94e-162: 469: 100.00		ANTP_DROME (161-375): 5.32e-31: 123: 32.56
+	Dm
		447312 TWIST_DROME (1-490): 3.94e-162: 469: 100.00		SCR_DROME (289-353): 5.65e-24: 104: 80.00
+	Dm
		80875 DIMM_DROME (213-479): 1.25e-32: 130: 18.52		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		611969 MYOD_DROME (248-460): 1.3e-32: 128: 23.21		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		950111 AMOS_DROME (221-420): 2.44e-31: 121: 25.12		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		950072 Q9VL05_DROME (348-437): 1e-21: 94.1: 37.36		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		80869 DIMM_DROME (213-479): 1.25e-32: 130: 18.52		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		611965 MYOD_DROME (248-460): 1.3e-32: 128: 23.21		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		668296 Q9VL05_DROME (348-437): 1e-21: 94.1: 37.36		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		367178 MYOD_DROME (248-460): 1.3e-32: 128: 23.21		ANTP_DROME (161-375): 5.32e-31: 123: 32.56
+	Hs
		524541 LYL1_HUMAN (271-486): 8.11e-28: 114: 23.66		HXD3_HUMAN (213-387): 2.01e-35: 136: 33.14
+	Hs
		446862 LYL1_HUMAN (271-486): 8.11e-28: 114: 23.66		HXD4_HUMAN (144-389): 1.64e-36: 135: 26.02
+	Hs
		595602 TWST1_HUMAN (319-483): 1.29e-28: 114: 37.58		HXA5_HUMAN (120-367): 8.65e-32: 123: 31.73
+	Dm
		1353790 Q9VHG3_DROME (260-443): 4.23e-30: 120: 22.75		Q9U984_DROME (241-366): 1.06e-30: 116: 26.98
+	Hs
		210859 TCF21_HUMAN (283-425): 5.13e-29: 114: 28.28		HXB6_HUMAN (161-372): 7.83e-31: 119: 31.13
+	Dm
		447321 MYOD_DROME (248-460): 1.3e-32: 128: 23.21		SCR_DROME (289-353): 5.65e-24: 104: 80.00
+	Hs
		567808 TAL1_HUMAN (344-421): 1.94e-23: 102: 40.48		HXB9_HUMAN (141-360): 6.75e-32: 122: 23.68
+	Dm
		1123855 Q59E67_DROME (364-433): 1.61e-13: 69.9: 38.03		Q9U984_DROME (241-366): 1.06e-30: 116: 26.98