HitPredict

Interactor 1: IF4A2 (P10630)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: Eif4a2

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 407 Mm			1 1161
+	Hs
		148596 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		149137 DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148373 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148153 DDX3Y_HUMAN (2-406): 3.31e-128: 385: 29.98		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148475 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148803 IF4A2_HUMAN (1-407): 2.49e-129: 380: 100.00		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		133870 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		724692 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		725100 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27