HitPredict

Interactor 1: IF4A2 (P10630)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: Eif4a2

Interactor 2: IF4H (Q9WUK2)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein homolog)
Gene: Eif4h

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 407 Mm			1 248
+	Hs
		892812 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		IF4H_HUMAN (1-248): 3.39e-54: 176: 98.79
+	Mm
		892964 IF4A1_MOUSE (3-407): 2.35e-159: 456: 89.88		IF4H_MOUSE (1-248): 9.36e-54: 175: 100.00
+	At
		97541 F4JEL4_ARATH (16-385): 6.12e-175: 496: 71.62		RBG7_ARATH (41-117): 1.05e-28: 108: 25.32
+	Hs
		618568 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		892791 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		PABP4_HUMAN (33-126): 1.24e-19: 89.4: 18.75
+	Hs
		516434 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Hs
		892803 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Mm
		857295 IF4A1_MOUSE (3-407): 2.35e-159: 456: 89.88		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Hs
		133883 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		181680 DDX3Y_HUMAN (2-406): 3.31e-128: 385: 29.98		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		1048159 DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20		HNRPD_HUMAN (2-213): 1.19e-23: 99.4: 15.49
+	Hs
		1054481 DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Hs
		571452 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Mm
		857323 DDX17_MOUSE (25-407): 6.02e-132: 395: 31.20		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Hs
		134018 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		PABP4_HUMAN (33-126): 1.24e-19: 89.4: 18.75
+	Mm
		857351 Q8BTS0_MOUSE (22-407): 5.62e-132: 393: 30.96		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Hs
		133858 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Hs
		516391 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Mm
		936480 DDX5_MOUSE (22-407): 3.04e-132: 394: 30.96		TIAR_MOUSE (10-215): 2.49e-14: 73.6: 9.62
+	Sc
		624037 DBP2_YEAST (22-405): 1.21e-131: 390: 32.65		NSR1_YEAST (30-150): 1.54e-09: 59.4: 21.26