Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.759

The method score is based on:

Property Details
Experiments 28514442, 19654187, 18500754, 29764935, 33139698, 33961781, 25864199, 17954934, 35063084, 14612456, 26269332
Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, nuclear magnetic resonance, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 758
Hs

1 646
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024