HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ODPB (P11177)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)
Gene: PDHB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 359
+	Rn
		581951 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ODPB_RAT (1-359): 8.94e-146: 417: 94.43
+	Rn
		94174 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ODPB_RAT (1-359): 8.94e-146: 417: 94.43
+	Mm
		498130 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ODPB_MOUSE (1-359): 1.82e-145: 417: 93.59
+	Hs
		496376 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TKT_HUMAN (13-357): 4.76e-100: 310: 17.09
+	Mm
		497940 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TKT_MOUSE (13-357): 9.76e-100: 309: 17.38
+	Hs
		505827 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ODPB_HUMAN (1-359): 9.81e-148: 422: 100.00
+	Dm
		1367389 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VHN7_DROME (13-357): 6.55e-101: 312: 17.95