HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ADT3 (P12236)
ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene: SLC25A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 298
+	Hs
		397240 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT2_HUMAN (1-297): 8.7e-111: 324: 92.26
+	Hs
		496183 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT1_HUMAN (1-298): 6.2e-111: 324: 88.26
+	Rn
		581991 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT1_RAT (1-298): 6e-112: 327: 89.60
+	Rn
		94213 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT1_RAT (1-298): 6e-112: 327: 89.60
+	Rn
		581994 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT2_RAT (1-297): 7.39e-111: 324: 91.58
+	Rn
		94216 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT2_RAT (1-297): 7.39e-111: 324: 91.58
+	Mm
		497947 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT1_MOUSE (1-298): 5.55e-112: 327: 88.93
+	Mm
		497951 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT2_MOUSE (1-297): 3.08e-111: 325: 91.25
+	Hs
		497760 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2513_HUMAN (3-271): 4.13e-43: 158: 18.96
+	Hs
		274476 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2512_HUMAN (12-119): 3.18e-19: 89.5: 22.02
+	Mm
		498076 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		S2512_MOUSE (12-119): 1.84e-19: 90.2: 22.94