HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KCRU (P12532)
Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK)
Gene: CKMT1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 417
+	Rn
		94225 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		Q5BJT9_RAT (1-417): 0: 667: 96.65
+	Rn
		581928 TAU_RAT (1-758): 4.86e-75: 260: 71.47		KCRU_RAT (1-417): 0: 662: 95.93
+	Hs
		496186 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KCRB_HUMAN (47-406): 0: 607: 69.81
+	Rn
		427025 TAU_RAT (1-758): 4.86e-75: 260: 71.47		KCRB_RAT (43-406): 0: 596: 68.22
+	Rn
		94118 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		KCRB_RAT (43-406): 0: 596: 68.22
+	Mm
		498016 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		KCRB_MOUSE (43-406): 0: 596: 68.49
+	Dm
		820802 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		KARG_DROME (45-400): 8.89e-179: 504: 41.94