HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019899 - enzyme binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1042
+	Rn
		513722 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AT2A2_RAT (1-1042): 0: 1050: 98.95
+	Rn
		94131 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AT2A2_RAT (1-1042): 0: 1050: 98.95
+	Mm
		223146 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		AT2A2_MOUSE (1-1042): 0: 1047: 98.66
+	Hs
		561576 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		AT2A2_HUMAN (1-1042): 0: 1060: 100.00
+	Hs
		392995 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AT1A1_HUMAN (3-997): 0: 797: 26.72
+	Hs
		496196 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AT1A3_HUMAN (4-997): 0: 794: 26.55
+	Hs
		496589 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AT1A2_HUMAN (3-997): 0: 788: 26.45
+	Hs
		496323 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AT2B4_HUMAN (3-1028): 0: 762: 25.75
+	Rn
		416147 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AT1A1_RAT (3-997): 0: 798: 26.82
+	Rn
		94112 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AT1A1_RAT (3-997): 0: 798: 26.82
+	Rn
		416169 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AT1A3_RAT (4-997): 0: 793: 26.55
+	Rn
		94114 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AT1A3_RAT (4-997): 0: 793: 26.55
+	Rn
		416161 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AT1A2_RAT (3-997): 0: 785: 26.26
+	Rn
		94113 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AT1A2_RAT (3-997): 0: 785: 26.26