HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 439
+	Hs
		496732 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60
+	Hs
		496733 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39
+	Hs
		92593 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		E9PM69_HUMAN (1-439): 1.92e-120: 358: 89.75
+	Hs
		496509 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59
+	Hs
		496648 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TERA_HUMAN (162-434): 9.21e-77: 256: 35.17
+	Mm
		498014 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TERA_MOUSE (162-434): 9.21e-77: 256: 35.17
+	Dm
		1359411 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9V405_DROME (6-438): 4.77e-130: 383: 37.64