HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0005874 - microtubule GO:0044297 - cell body
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 556
+	Hs
		496556 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Rn
		582014 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPE_RAT (4-532): 0: 622: 31.84
+	Rn
		94240 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPE_RAT (4-532): 0: 622: 31.84
+	Rn
		582024 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPD_RAT (8-531): 0: 611: 32.02
+	Rn
		94250 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPD_RAT (8-531): 0: 611: 32.02
+	Mm
		498006 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPE_MOUSE (4-532): 0: 623: 32.03
+	Mm
		497911 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPA_MOUSE (1-556): 0: 622: 96.40
+	Hs
		497502 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		496545 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Mm
		498007 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPG_MOUSE (5-550): 0: 593: 32.48
+	Dm
		820679 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		TCPG_DROME (5-551): 0: 546: 29.98
+	Mm
		498005 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPB_MOUSE (3-542): 6.18e-83: 270: 35.04
+	Dm
		1370374 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9W392_DROME (14-538): 9.77e-89: 285: 35.22