HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ITIH2 (P19823)
Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32812023, 26402096, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 946
+	Hs
		497166 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		Q5T985_HUMAN (1-946): 0: 1131: 98.84
+	Hs
		496903 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ITIH3_HUMAN (53-940): 0: 994: 39.04
+	Hs
		497021 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ITIH4_HUMAN (64-919): 0: 785: 33.23
+	Hs
		496634 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CA2D1_HUMAN (308-499): 6.03e-42: 168: 21.54