HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: VATB2 (P21281)
V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)
Gene: ATP6V1B2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 511
+	Rn
		581968 TAU_RAT (1-758): 4.86e-75: 260: 71.47		VATB2_RAT (1-511): 0: 644: 99.02
+	Rn
		94191 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		VATB2_RAT (1-511): 0: 644: 99.02
+	Hs
		415179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ATPB_HUMAN (1-503): 9.79e-171: 494: 22.97
+	Rn
		499197 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ATPB_RAT (1-503): 3.16e-171: 495: 22.39
+	Rn
		94127 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ATPB_RAT (1-503): 3.16e-171: 495: 22.39
+	Dm
		54308 A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47		VATB_DROME (24-508): 0: 599: 89.92