HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CSRP1 (P21291)
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Gene: CSRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 193
+	Hs
		497742 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIMA1_HUMAN (3-117): 9.06e-21: 91: 27.83
+	Hs
		300985 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM3_HUMAN (7-169): 1.17e-20: 90.5: 14.97
+	Hs
		497180 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM2_HUMAN (7-170): 3.74e-19: 86.3: 14.52
+	Hs
		496619 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CRIP2_HUMAN (3-81): 6.3e-17: 77: 37.50
+	Hs
		150508 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM1_HUMAN (119-192): 6.1e-14: 71.2: 27.03
+	Hs
		496577 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CRIP1_HUMAN (118-183): 9.08e-14: 65.5: 52.24
+	Hs
		1056843 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CSRP2_HUMAN (1-193): 2.04e-46: 152: 79.28
+	Hs
		1056876 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MICA3_HUMAN (3-118): 4.43e-18: 83.3: 27.94
+	Ce
		107557 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		G5EFG1_CAEEL (67-193): 3.21e-22: 95.1: 15.00
+	Dm
		973530 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q2PDT4_DROME (6-67): 1.53e-10: 61.2: 27.42
+	Dm
		973532 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q8INW7_DROME (6-67): 3.02e-10: 60.4: 27.42