HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: S10A1 (P23297)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 94
+	Hs
		497264 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HORN_HUMAN (1-88): 6.3e-32: 118: 35.23
+	Hs
		496690 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AA_HUMAN (1-91): 5.26e-33: 111: 48.35
+	Hs
		497147 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA2_HUMAN (3-93): 1.44e-27: 106: 37.36
+	Hs
		380723 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S100B_HUMAN (3-93): 1.37e-29: 102: 58.24
+	Hs
		416341 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A9_HUMAN (3-92): 4.24e-29: 102: 37.36
+	Hs
		396671 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A8_HUMAN (1-94): 1.35e-27: 97.6: 36.17
+	Hs
		416558 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A6_HUMAN (1-88): 1.92e-26: 94.5: 44.32
+	Hs
		496287 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA_HUMAN (1-94): 4.87e-22: 90.3: 35.11
+	Hs
		497435 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AG_HUMAN (3-93): 4.23e-23: 86.4: 33.70
+	Hs
		497487 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AD_HUMAN (3-84): 2.15e-21: 82.2: 40.24
+	Hs
		152595 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		S10A2_HUMAN (1-90): 1.74e-31: 107: 52.22
+	Bt
		361268 TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00		S100B_BOVIN (3-93): 4.24e-30: 104: 57.14