HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RS3 (P23396)
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18)
Gene: RPS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

The method score is based on:

Property	Details
Experiments	32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 8 others more... GO:0005886 - plasma membrane GO:0006974 - DNA damage response GO:0008017 - microtubule binding GO:0019899 - enzyme binding GO:0019901 - protein kinase binding GO:0031116 - positive regulation of microtubule polymerization GO:0034614 - cellular response to reactive oxygen species GO:0051879 - Hsp90 protein binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	758
Hs

1	243

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024