Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.657

The method score is based on:

Property Details
Experiments 26269332, 29966762, 35063084
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0034063 - stress granule assembly
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 758
Hs

1 483
+ Hs
+ Hs
+ Hs
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+ Mm
+ Mm
+ Mm
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+ Dm

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Last updated: 15 Jul 2024