HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 557
+	Hs
		320962 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PTBP3_HUMAN (1-557): 1.83e-101: 318: 74.01
+	Hs
		497765 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PTBP2_HUMAN (1-557): 2.33e-92: 294: 68.40
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (3-375): 1.46e-44: 169: 13.58
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (3-378): 1.16e-43: 166: 10.62
+	Hs
		320963 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PTBP3_HUMAN (1-557): 1.83e-101: 318: 74.01
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (3-375): 1.43e-44: 169: 13.58
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (3-375): 1.43e-44: 169: 13.58
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (366-555): 1.49e-28: 119: 17.28
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (3-369): 6.13e-45: 170: 11.77
+	Hs
		446492 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SNRPA_HUMAN (361-471): 6.95e-19: 89.1: 16.38
+	Mm
		498050 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ELAV4_MOUSE (366-555): 1.6e-28: 119: 17.28
+	Hs
		496218 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPL_HUMAN (15-252): 9.17e-10: 63.4: 13.31
+	Mm
		498097 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HNRPL_MOUSE (15-252): 4.72e-10: 64.1: 13.31
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (3-375): 1.46e-44: 169: 13.58