HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	19681044, 18467332
Identification Methods	affinity chromatography technology, unspecified method, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 724
+	Hs
		653918 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		497161 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46
+	Hs
		497654 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RHG35_HUMAN (89-325): 8.1e-55: 206: 23.46
+	Hs
		253306 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SRGP2_HUMAN (118-668): 3.41e-54: 203: 13.78
+	Hs
		497708 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RHG23_HUMAN (40-369): 2.83e-52: 198: 16.80
+	Rn
		88879 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SRGP2_RAT (118-668): 3.29e-56: 209: 13.96
+	Rn
		88880 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SRGP2_RAT (118-668): 3.29e-56: 209: 13.96
+	Hs
		1133704 PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11		RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46