HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 263
+	Hs
		496366 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64
+	Hs
		497478 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82
+	Hs
		496337 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSA2_HUMAN (30-259): 6.04e-80: 242: 18.64
+	Hs
		496339 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSA4_HUMAN (32-255): 1.03e-79: 242: 18.22
+	Hs
		496368 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSB6_HUMAN (43-245): 4.34e-77: 235: 31.37
+	Dm
		1213759 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q8INY4_DROME (18-261): 8.91e-79: 240: 43.58