HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 332
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (8-329): 5.64e-12: 69.1: 9.41
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (5-331): 3.64e-19: 90.3: 18.21
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (5-331): 3.67e-19: 90.3: 18.21
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (2-330): 4.78e-09: 59.8: 10.09
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (2-330): 4.78e-09: 59.8: 10.09
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (2-313): 2.54e-09: 60.6: 12.89
+	Hs
		297814 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Hs
		1056937 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CHAP1_HUMAN (10-330): 1.59e-09: 61.1: 9.35
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57
+	Dm
		375663 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		RPB1_DROME (36-332): 6.22e-25: 107: 8.64
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (8-311): 1.96e-09: 61.3: 9.39
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (1-315): 3.36e-09: 60.6: 13.02
+	Hs
		1336185 MAGE1_HUMAN (222-587): 4.83e-09: 61.9: 16.22		MAGE1_HUMAN (3-326): 4.56e-11: 66: 11.66