HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 359
+	Hs
		496575 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAQ_HUMAN (1-359): 1.3e-168: 475: 90.25
+	Hs
		496793 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI1_HUMAN (7-358): 3.66e-163: 462: 51.70
+	Hs
		450973 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAO_HUMAN (7-358): 1.96e-161: 457: 50.28
+	Hs
		391314 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14
+	Hs
		444653 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57
+	Hs
		325959 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNA14_HUMAN (9-359): 2.8e-158: 449: 82.34
+	Hs
		496792 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83
+	Mm
		497926 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAQ_MOUSE (1-359): 8.51e-169: 476: 90.25
+	Hs
		496266 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAZ_HUMAN (7-358): 3e-145: 416: 46.76
+	Mm
		497925 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNA11_MOUSE (1-359): 1.32e-166: 470: 98.05
+	Rn
		581959 TAU_RAT (1-758): 4.86e-75: 260: 71.47		GNAO_RAT (7-358): 8.34e-160: 453: 49.44
+	Rn
		94182 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		GNAO_RAT (7-358): 8.34e-160: 453: 49.44
+	Hs
		497017 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNA13_HUMAN (8-358): 1.24e-143: 413: 45.00
+	Mm
		70618 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAI1_MOUSE (7-358): 3.66e-163: 462: 51.70
+	Mm
		444631 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAI2_MOUSE (7-358): 7.1e-160: 453: 50.42
+	Mm
		250846 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAZ_MOUSE (7-358): 8.82e-146: 417: 46.76