HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AL4A1 (P30038)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: ALDH4A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 563
+	Hs
		496398 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1B1_HUMAN (35-556): 0: 605: 23.25
+	Hs
		334346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1A1_HUMAN (53-556): 0: 601: 23.58
+	Hs
		396438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ALDH2_HUMAN (27-556): 0: 589: 22.43
+	Hs
		277192 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1L1_HUMAN (48-551): 6.05e-180: 532: 22.70
+	Hs
		496552 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL9A1_HUMAN (67-558): 1.64e-178: 514: 23.80
+	Dm
		1369989 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VLC5_DROME (27-556): 0: 582: 20.56