HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ERP29 (P30040)
Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31)
Gene: ERP29

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010629 - negative regulation of gene expression GO:0051087 - protein-folding chaperone binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 261
+	Hs
		496390 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49
+	Hs
		497046 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48
+	Hs
		423114 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17
+	Hs
		496945 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA2_HUMAN (23-151): 1.93e-27: 112: 16.67
+	Hs
		497310 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TXND5_HUMAN (57-255): 6.77e-20: 89.8: 15.27