HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 505
+	Hs
		423114 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68
+	Hs
		497523 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ERP44_HUMAN (368-496): 4.41e-25: 109: 21.64
+	Hs
		496945 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA2_HUMAN (356-501): 1e-23: 106: 22.30
+	Hs
		497046 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PDIA6_HUMAN (385-471): 3.13e-10: 64.3: 40.91
+	Hs
		110813 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H7BZJ3_HUMAN (384-453): 1.29e-09: 58.5: 38.36
+	Hs
		1243836 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		ERP44_HUMAN (368-496): 4.41e-25: 109: 21.64