HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: COR1A (P31146)
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)
Gene: CORO1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0030424 - axon
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 461
+	Hs
		497516 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR1B_HUMAN (1-458): 6.66e-116: 350: 63.90
+	Hs
		1163311 MAGE1_HUMAN (222-587): 4.83e-09: 61.9: 16.22		CORO6_HUMAN (1-458): 1.61e-123: 369: 67.10
+	Hs
		497815 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR2B_HUMAN (1-214): 1.46e-23: 104: 12.39
+	Hs
		497789 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR1C_HUMAN (2-210): 6.55e-23: 103: 11.77
+	Hs
		496923 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBBP4_HUMAN (30-164): 1.26e-14: 77.4: 19.72
+	Hs
		1056932 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SNR40_HUMAN (2-158): 5.82e-29: 118: 16.15
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (296-386): 4.4e-10: 63: 6.45
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (3-110): 7.1e-17: 83.4: 16.96
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (3-110): 7.1e-17: 83.4: 16.96
+	Dm
		973546 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9W3W1_DROME (2-200): 1.15e-10: 66: 12.80
+	Dm
		90207 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		D6W4T8_DROME (2-200): 1.78e-10: 65.7: 12.80