HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AKT2 (P31751)
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC protein kinase beta) (RAC-PK-beta)
Gene: AKT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 481
+	Hs
		496407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		496879 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCE_HUMAN (57-475): 3.59e-147: 439: 39.10
+	Hs
		408538 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		496317 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6B1_HUMAN (134-478): 1.35e-146: 431: 44.13
+	Hs
		116961 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SGK1_HUMAN (102-478): 3.87e-145: 423: 43.68
+	Hs
		496248 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KAPCA_HUMAN (141-447): 2.12e-144: 419: 41.69
+	Rn
		581978 TAU_RAT (1-758): 4.86e-75: 260: 71.47		KPCB_RAT (72-478): 2.35e-150: 445: 40.39
+	Rn
		94201 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		KPCB_RAT (72-478): 2.35e-150: 445: 40.39
+	Hs
		152597 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		497071 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A1_HUMAN (55-456): 2.33e-109: 342: 23.13
+	Hs
		496604 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A3_HUMAN (55-452): 8.73e-107: 335: 23.36
+	Hs
		270366 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A5_HUMAN (60-406): 1.32e-104: 331: 27.25
+	Hs
		496492 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCI_HUMAN (142-475): 3.18e-106: 330: 46.96
+	Hs
		496245 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCA_HUMAN (146-475): 2.81e-103: 324: 47.43
+	Hs
		496900 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCZ_HUMAN (149-475): 9.44e-101: 315: 46.43
+	Hs
		503261 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		KAPCA_HUMAN (141-447): 2.12e-144: 419: 41.69
+	Bt
		337290 TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00		KAPCA_BOVIN (141-447): 1.04e-143: 417: 41.04