HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HNRH3 (P31942)
Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)
Gene: HNRNPH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 346
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (18-287): 4.45e-50: 178: 13.77
+	Hs
		496269 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NUCL_HUMAN (5-254): 2.01e-21: 97.3: 17.11
+	Hs
		496661 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH2_HUMAN (9-136): 3.82e-13: 71.9: 28.46
+	Hs
		496413 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH1_HUMAN (9-136): 7.11e-13: 71.1: 27.69
+	Hs
		496614 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPF_HUMAN (9-197): 5.95e-12: 68: 20.40
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (187-276): 1.9e-10: 64.2: 18.28
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (189-276): 1.96e-10: 63.8: 17.58
+	Mm
		449409 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		NUCL_MOUSE (5-254): 1.69e-21: 97.7: 16.41
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (187-276): 2.08e-10: 63.8: 18.28
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (187-276): 2.08e-10: 63.8: 18.28
+	Hs
		582292 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		NUCL_HUMAN (5-254): 2.01e-21: 97.3: 17.11
+	Hs
		582417 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		NUCL_HUMAN (5-254): 2.01e-21: 97.3: 17.11
+	Dm
		1366083 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VGH5_DROME (17-89): 4.17e-10: 63: 31.51
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (187-276): 1.9e-10: 64.2: 18.28