HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	32812023, 35063084, 15953362, 26269332
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0036464 - cytoplasmic ribonucleoprotein granule
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 433
+	Hs
		496509 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93
+	Hs
		496733 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS8_HUMAN (35-430): 2.5e-119: 355: 45.20
+	Hs
		496752 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46