HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 574
+	Hs
		496842 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ARF1_HUMAN (390-569): 5.89e-71: 227: 57.22
+	Hs
		496257 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ARF4_HUMAN (393-568): 1.47e-70: 226: 55.11
+	Hs
		496843 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ARF5_HUMAN (392-568): 1.63e-69: 223: 55.37
+	Mm
		497968 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ARF4_MOUSE (398-568): 2.26e-85: 264: 56.14
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (397-569): 2.41e-61: 203: 15.17
+	Hs
		496707 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ARF3_HUMAN (390-569): 5.58e-61: 201: 56.67
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (397-569): 7.05e-60: 199: 15.17
+	Hs
		496594 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB13_HUMAN (397-568): 2.33e-58: 195: 19.21
+	Hs
		108975 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H0YNE9_HUMAN (397-568): 2.29e-58: 194: 20.34
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (397-568): 4.19e-58: 194: 20.34
+	Rn
		581981 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ARF2_RAT (392-569): 2.05e-71: 228: 57.30
+	Rn
		94204 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ARF2_RAT (392-569): 2.05e-71: 228: 57.30
+	Rn
		581962 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ARF3_RAT (390-569): 5.58e-61: 201: 56.67
+	Rn
		94185 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ARF3_RAT (390-569): 5.58e-61: 201: 56.67
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (397-569): 2.41e-61: 203: 15.17
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (397-569): 1.59e-59: 198: 15.17
+	Dm
		897470 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		ARF1_DROME (392-570): 3.25e-72: 230: 59.22