HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.619

The method score is based on:

Property Details
Experiments 16262633, 35063084
Identification Methods enzymatic study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 758
Hs

1 323
+ Hs
+ Hs
+ Mm
+ Mm
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+ Hs
+ Hs
+ Mm
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+ Dm
+ Dm
+ Mm
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+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024