HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: VATA (P38606)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)
Gene: ATP6V1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 617
+	Mm
		840051 SYNJ1_MOUSE (129-637): 3.11e-11: 69.3: 11.20		VATA_MOUSE (1-617): 0: 837: 98.06
+	Hs
		415179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ATPB_HUMAN (140-565): 5.22e-129: 391: 23.08
+	Hs
		496335 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ATPA_HUMAN (41-610): 1.99e-126: 385: 18.34
+	Rn
		499197 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ATPB_RAT (140-565): 2.95e-129: 391: 23.08
+	Rn
		94127 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ATPB_RAT (140-565): 2.95e-129: 391: 23.08
+	Rn
		554780 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ATPA_RAT (41-609): 7.46e-126: 384: 18.37
+	Rn
		94139 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ATPA_RAT (41-609): 7.46e-126: 384: 18.37
+	Dm
		54308 A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47		VATB_DROME (140-542): 4.92e-124: 377: 20.53