HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 531
+	Hs
		497502 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		496556 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		496545 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		497362 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPW_HUMAN (1-530): 0: 542: 85.85
+	Rn
		582014 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPE_RAT (3-528): 0: 543: 30.28
+	Rn
		94240 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPE_RAT (3-528): 0: 543: 30.28
+	Mm
		498007 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPG_MOUSE (3-528): 0: 558: 28.14
+	Rn
		582024 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPD_RAT (12-522): 0: 538: 29.26
+	Rn
		94250 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPD_RAT (12-522): 0: 538: 29.26
+	Mm
		498043 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPW_MOUSE (1-530): 0: 551: 81.32
+	Mm
		498006 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPE_MOUSE (3-528): 0: 542: 30.84