HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PERI (P41219)
Peripherin (Neurofilament 4)
Gene: PRPH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 470
+	Hs
		443287 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		VIME_HUMAN (10-458): 2.68e-145: 425: 56.79
+	Hs
		496206 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GFAP_HUMAN (77-459): 1.36e-112: 340: 57.44
+	Rn
		581945 TAU_RAT (1-758): 4.86e-75: 260: 71.47		GFAP_RAT (77-459): 4.16e-110: 333: 56.66
+	Rn
		94169 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		GFAP_RAT (77-459): 4.16e-110: 333: 56.66
+	Hs
		497096 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AINX_HUMAN (13-430): 5.73e-93: 292: 49.41
+	Mm
		372929 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GFAP_MOUSE (77-459): 4.12e-110: 333: 56.14
+	Hs
		422133 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NFL_HUMAN (76-408): 1.05e-78: 256: 52.54
+	Hs
		422332 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NFM_HUMAN (15-408): 5.91e-73: 249: 43.81
+	Rn
		581925 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AINX_RAT (13-430): 1.55e-90: 286: 50.59
+	Rn
		94148 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AINX_RAT (13-430): 1.55e-90: 286: 50.59
+	Hs
		496199 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		K2C5_HUMAN (62-410): 2.66e-73: 243: 35.98
+	Hs
		359457 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		K2C6A_HUMAN (62-426): 1.79e-72: 240: 33.06
+	Rn
		581922 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFL_RAT (76-408): 5.18e-79: 257: 52.24
+	Rn
		94145 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NFL_RAT (76-408): 5.18e-79: 257: 52.24
+	Rn
		522304 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFM_RAT (89-408): 9.99e-71: 241: 47.83
+	Rn
		94135 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NFM_RAT (89-408): 9.99e-71: 241: 47.83
+	Mm
		440283 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		NFM_MOUSE (15-408): 9.26e-71: 242: 43.28
+	Hs
		422135 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		NFL_HUMAN (76-408): 1.05e-78: 256: 52.54
+	Rn
		562617 NFH_RAT (311-752): 2.44e-13: 76.2: 12.22		NFL_RAT (76-408): 5.18e-79: 257: 52.24
+	Hs
		203197 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		K2C8_HUMAN (92-422): 1.6e-60: 207: 40.54