HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RECQ1 (P46063)
ATP-dependent DNA helicase Q1 (EC 5.6.2.4) (DNA 3'-5' helicase Q1) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)
Gene: RECQL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 649
+	Hs
		497386 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX17_HUMAN (8-505): 7.91e-129: 398: 14.54
+	Hs
		496251 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX5_HUMAN (9-468): 1.14e-125: 386: 15.97
+	Hs
		497260 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX42_HUMAN (2-458): 4.83e-115: 368: 14.44
+	Hs
		133854 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX3X_HUMAN (16-447): 1.24e-115: 362: 12.66
+	Hs
		295531 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		RECQ5_HUMAN (71-487): 1.15e-178: 535: 36.65
+	Mm
		498030 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DDX17_MOUSE (8-505): 3.67e-128: 394: 14.54
+	Mm
		498084 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q8BTS0_MOUSE (9-468): 1.95e-125: 386: 15.76
+	Mm
		498056 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DDX3Y_MOUSE (15-473): 1.24e-114: 359: 12.09
+	Hs
		801879 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		RECQ1_HUMAN (1-649): 1.14e-156: 467: 100.00
+	Hs
		1050599 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		WRN_HUMAN (11-642): 8.49e-137: 436: 26.10
+	Hs
		653941 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		BLM_HUMAN (48-617): 4.7e-125: 404: 35.01
+	Hs
		295083 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		RECQ4_HUMAN (76-453): 5.17e-127: 405: 30.39