HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 744
+	Hs
		111062 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		I3L0N3_HUMAN (6-744): 0: 564: 100.00
+	Rn
		582037 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NSF_RAT (1-744): 0: 572: 97.85
+	Rn
		94263 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NSF_RAT (1-744): 0: 572: 97.85
+	Dm
		804042 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		NSF1_DROME (6-741): 5.33e-169: 505: 62.47
+	Hs
		496648 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TERA_HUMAN (146-479): 5.59e-69: 244: 31.05
+	Mm
		498014 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TERA_MOUSE (146-479): 5.59e-69: 244: 31.05