HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KC1D (P48730)
Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)
Gene: CSNK1D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	14761950, 35063084, 17101137, 19014373, 16618118
Identification Methods	affinity chromatography technology, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:1990090 - cellular response to nerve growth factor stimulus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 415
+	Hs
		496547 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KC1A_HUMAN (2-325): 7.17e-123: 361: 69.44
+	Hs
		92372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		E9PBG7_HUMAN (4-399): 7.52e-118: 354: 16.38
+	Rn
		987567 MAP4_RAT (60-757): 1.97e-10: 66.6: 8.17		KC1D_RAT (1-415): 6.49e-142: 412: 99.76