HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MASP1 (P48740)
Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain]
Gene: MASP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8990203
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 699
+	Hs
		341183 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HPT_HUMAN (297-695): 4.71e-100: 314: 27.92
+	Hs
		341132 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		THRB_HUMAN (131-695): 8.96e-89: 292: 21.26
+	Hs
		497327 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TRY6_HUMAN (442-699): 4.72e-87: 275: 30.77
+	Hs
		496427 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TRY3_HUMAN (422-699): 3.83e-84: 269: 29.64
+	Hs
		497555 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TMPSD_HUMAN (302-699): 2.41e-79: 265: 20.60