HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AL9A1 (P49189)
4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Formaldehyde dehydrogenase) (EC 1.2.1.46) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed]
Gene: ALDH9A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 494
+	Hs
		334346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1A1_HUMAN (10-492): 0: 634: 39.06
+	Hs
		496398 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1B1_HUMAN (11-492): 0: 626: 39.34
+	Hs
		396438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ALDH2_HUMAN (12-492): 0: 622: 41.27
+	Hs
		277192 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AL1L1_HUMAN (1-487): 0: 561: 39.16
+	Dm
		1369989 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VLC5_DROME (11-492): 0: 617: 39.43